Who won: Rental Agreement for a high sensitivity Tandem Mass Spectrometer - High Performance Liquid Chromatography system for analysis of hormones biological fluids.

About this contract

The CUH Blood Sciences Biochemical Genetics Unit is looking to replace a high sensitivity Triple Quadrupole Tandem Mass Spectrometer (TMS) coupled to an ultra-high pressure liquid chromatography (HPLC) system. This system runs 10 methods including newborn blood spot analysis that were developed either in-house or in conjunction with suppliers. The Blood Sciences labs currently have four Sciex triple quadrupole tandem mass spectrometers (TMS) linked to Shimadzu or Sciex (Exion) liquid chromatography (HPLC) systems. This includes the system that we are replacing. The combined laboratories currently process around 120,000 samples a year through the four LC-Tandem Mass Spectrometer systems. Results generated from the systems are from technically/clinically validated methods and are used for diagnosis of endocrine and metabolic disorders, as well as for neonatal screening tests. The replacement system must be capable of quantitation of a range of metabolites in human serum, urine and blood spot and therefore must be capable of using Chemoview to quantitate the newborn screening blood spot assays. Some of the analytes are at nmol/L concentrations in human serum e.g. urine matanepherine

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