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Located on the Harwell Science & Innovation Campus in Oxfordshire, Diamond Light Source (DLS) is a leading-edge facility for science, engineering and innovation. DLS allows researchers from academia and industry to investigate the structure and behaviour of the world around us at the atomic and molecular level. To continue delivering the world-changing science that Diamond enables, the facility is being upgraded to Diamond-II, a co-ordinated programme of development that combines a major machine upgrade with new instruments and complementary improvements to optics, detectors, sample environment and delivery capabilities, and computing, as well as integrated and correlative methods. This will be transformative in speed and spatial resolution and will offer users streamlined access to enhanced instruments for life and physical sciences. The K04 beamline will be an ultra-high throughput Macromolecular Crystallography beamline optimised for the study of biological samples (fragment screening) to support the XChem facility in early-stage lead drug discovery. K04 will greatly increase DLS's capacity to carry out XChem experiments by up to 20x, accelerating drug discovery timelines and re
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